Ni izihe nyungu 3 z'umubiri za Vitamine B1?

Vitamine B1, ubundi bita thiamine, ninyongera yingirakamaro ifata igice cyingenzi mugukomeza kubaho neza. Iyi ntungamubiri y'amazi-yashonga ningirakamaro mubikorwa bitandukanye byumubiri kandi itanga ibyiza bitandukanye. Ntabwo iyobora gusa murwego rwibitekerezo muguhindura karbike muri glucose nyamara byongeye bigashyigikira ubushobozi bwibitekerezo, bifasha mukuzamura kwibuka no kwibanda. Byongeye kandi, thiamine ningirakamaro mugukomeza sisitemu ikomeye, kugabanya urusimbi rwibibazo byubwonko. Muri uyu mufasha wuzuye, tuzasesengura ibyiza bitatu byumubiri byaifu ya vitamine B1hanyuma wibire mubisobanuro byacyo muri rusange kuvuga iterambere.

Umusaruro w'ingufu na Metabolism

Kimwe mu byiza byingenzi bya vitamine B1 nakazi kayo mukurema ingufu no gusya. Iyi nyongera yibanze igenda nka coenzyme muburyo butandukanye bwo guhinduranya, ifasha guhindura karubone, proteyine, hamwe namavuta mumbaraga zikoreshwa mumubiri. Mugukorana nibisubizo byibinyabuzima, thiamine yemeza ko selile zibona imbaraga zikeneye gukora neza. Ibi ni ingirakamaro cyane cyane ku ngingo zifite ingufu nyinshi, urugero, umutima n'ubwonko, biterwa cyane no gutanga ingufu zihamye. Byongeye kandi, urwego rwa thiamine rushimishije rushobora kunoza imikorere nyayo no kugabanya umunaniro, wongeyeho muri rusange.

Glucose Metabolism

Vitamine B1 ifite uruhare runini muri glucose metabolism. Ifasha mukumena glucose, ituma selile zikoresha isukari yoroshye kugirango itange ingufu. Ubu buryo ni ingenzi cyane mu gukomeza isukari mu maraso ihamye no gutanga ingufu zihoraho mu ngingo no mu ngingo z'umubiri.

Imikorere ya Mitochondrial

Thiamine igira uruhare runini mugushigikira imikorere ya mito-iyambere. Mitochondria bakunze kwitwa imbaraga zingirabuzimafatizo, ishinzwe kubyara ATP (adenosine triphosphate), ifaranga ryibanze ryumubiri. Vitamine B1 ifasha kwemeza ko mitochondriya ishobora gutanga ingufu neza, igafasha ubuzima rusange bwimikorere nimikorere.

Imikino ngororamubiri

Kubera ishyirahamwe ryayo mu igogora ryingufu,vitamine B1irashobora kuba ingirakamaro cyane kubanywanyi kandi mubyukuri abantu bafite imbaraga. Urwego rwa thiamine rushimishije rushobora gufasha mugutezimbere kwihangana, kugabanya intege nke, no kunoza imikorere yimikino rusange. Abanywanyi benshi bahitamo inyongera ya vitamine B1, nka pome ya vitamine B1 cyangwavitamine B1 ibinini, kugirango bafashe imbaraga zabo bakeneye mugihe cyinyigisho zidasanzwe cyangwa guhangana.

Ubuzima bwa sisitemu yubuzima

Iyindi nyungu ikomeye ya vitamine B1 ningaruka nziza kuri sisitemu yimyumvire. Thiamine ningirakamaro mugukurikiza imikorere yemewe yimitsi yose mumubiri. Ifata igice cyibanze mubumwe bwa synaps, nibyingenzi mukwandikirana kwingirangingo. Urwego rwa thiamine ruhagije rufasha kurinda kwangirika kwimitsi no gushyigikira ubushobozi bwibitekerezo nko kwibuka no kwibanda. Uretse ibyo, kubura thiamine birashobora kwihutisha ibibazo by’imitsi, bishimangira akamaro kayo mu bihe by’amashyamba nka Wernicke-Korsakoff. Muri rusange, vitamine B1 ni ngombwa mu gushyigikira uburyo bukomeye bwo kumva no kwemeza ubwenge bwiza.

Neurotransmitter Synthesis

Vitamine B1 ifata igice cyingenzi muguhuza synaps, aribwo butumwa bwoherejwe bwohereza ibimenyetso hagati ya selile nervice. Iyi synaps ningirakamaro kubushobozi butandukanye bwo mumutwe, harimo kwibuka, kwiga, hamwe nubuyobozi bwashizeho ibitekerezo. Urwego rwa thiamine rushimishije rufasha mukwemeza kurema neza no kuza kwa synaps, bifasha muri rusange kuvuga ubwonko bwubwonko n'ubushobozi.

Kubungabunga Sheel

Thiamine ni ngombwa mu kubungabunga sheel ya myelin, igikingira kirinda fibre nervice. Sheel ya myelin ikora nka insulator, itanga uburyo bwihuse kandi bunoze bwo gukwirakwiza amashanyarazi kumasemburo ya nervice. Mugushyigikira ubuzima bwa myelin, vitamine B1 ifasha kugumana imikorere myiza yumutima no gutumanaho mumubiri.

Neuroprotection

Ubushakashatsi bwerekana ko vitamine B1 ishobora kuba ifite imitekerereze ya neuroprotective, ishobora gufasha mu gukumira cyangwa kudindiza iterambere ry’indwara zimwe na zimwe z’imitsi. Mugihe hakenewe ubushakashatsi bwinshi kugirango twumve neza uburyo bwa neuroprotective, bukomeza urugero rwa thiamine ihagije binyuze mumirire cyangwa inyongera nka ifu ya vitamine B1cyangwa vitamine B1 ibinini bishobora kugira uruhare mubuzima bwubwonko bwigihe kirekire.

Ubuzima bwumutima

Inyungu ya gatatu ikomeye yumubiri wa vitamine B1 ningaruka nziza kumibereho yumutima nimiyoboro. Thiamine ifata igice cyihutirwa mugukomeza umutima uhamye no gutembera. Igenzura imiyoboro y'amaraso ishyigikira ubushobozi bwemewe bwimitsi no guteza imbere igogorwa ryingufu zifatika mumitsi yumutima. Na none, dogere zishimishije za vitamine B1 zirashobora gufasha mubihe byo gutera amashyamba nko kumeneka k'umutima n'imitsi kandi bishobora kugabanya urusimbi rwa hypertension. Mu kwemeza ko umutima ufite imbaraga zikenewe kuri siphon mubyukuri, thiamine yongerera ubuzima bwiza bwumutima nimiyoboro yimitsi kandi igateza imbere kwihangana, gushyigikira imibereho.

Imikorere y'umutima

Vitamine B1 ni ngombwa mu mikorere myiza y'umutima. Ifasha gushyigikira ubushobozi bwimitsi yumutima ubushobozi bwo kwandura no kuvoma amaraso neza mumubiri. Urwego rwa thiamine ruhagije rushobora kugira uruhare mu gukomeza injyana yumutima nzima hamwe nimikorere yumutima muri rusange.

Amabwiriza Yumuvuduko wamaraso

Ubushakashatsi bumwe bwerekana ko vitamine B1 ishobora kugira uruhare mu kugabanya umuvuduko wamaraso. Mugihe hakenewe ubushakashatsi bwinshi kugirango dusobanukirwe neza iyi sano, kugumana urugero rwiza rwa thiamine binyuze mumirire cyangwa inyongera nka vitamine B1 ifu cyangwavitamine B1 ibininiirashobora kugira uruhare mukurwego rwumuvuduko wamaraso.

Imikorere ya Endothelia

Thiamine igira uruhare mu kubungabunga ubuzima bwa endotelium, imbere mu mitsi y'amaraso. Endotelium nzima ningirakamaro mugutembera neza kwamaraso no mumikorere y'amaraso. Mugushyigikira ubuzima bwa endoteliyale, vitamine B1 irashobora kugira uruhare mubuzima bwiza bwumutima nimiyoboro yumutima kandi igafasha kugabanya ibyago byibibazo bimwe na bimwe byumutima.

Umwanzuro

Vitamine B1 itanga inyungu zingenzi, zirimo gushyigikira umusaruro w'ingufu, metabolisme, ubuzima bwa sisitemu y'imitsi, n'imikorere y'umutima. Mugihe ushobora kubona thiamine mumirire yuzuye ikungahaye ku binyampeke n'ibinyamisogwe, abantu bamwe bashobora kungukirwa ninyongera nkaifu ya vitamine B1 cyangwa ibinini byo gufata neza. Nibyingenzi kugisha inama inzobere mubuzima mbere yo gutangira inyongera nshya kugirango umenye dosiye ikwiye kubyo ukeneye. Ukeneye ibisobanuro birambuye kubyerekeye vitamine B1 nziza, hamagara Xi'an tgybio Biotech Co., Ltd kuriRebecca@tgybio.com. Turashobora gutanga ibinini bya Vitamine b1. Uruganda rwacu rushobora kandi gutanga OEM / ODM Serivisi imwe ihagarara, harimo gupakira hamwe na labels.

Reba

Martel, J. L., & Franklin, D. S. (2022). Vitamine B1 (Thiamine). Gusohora.

Bettendorff, L. (2012). Thiamine. Mubumenyi bwa none mumirire (pp. 261-279). Wiley-Blackwell.

Lonsdale, D. (2006). Isubiramo ryibinyabuzima, metabolism nibyiza byubuvuzi bya thiamin (e) nibiyikomokaho. Ubuvuzi bushingiye ku bimenyetso byuzuzanya n'ubundi buryo, 3 (1), 49-59.

Manzetti, S., Zhang, J., & van der Spoel, D. (2014). Imikorere ya Thiamin, metabolism, gufata, no gutwara. Ibinyabuzima, 53 (5), 821-835.

Whitfield, KC, Bourassa, MW, Adamolekun, B., Bergeron, G., Bettendorff, L., Brown, KH, ... & Combs Jr, GF (2018). Indwara ya Thiamine: kwisuzumisha, ubwinshi, hamwe nigishushanyo mbonera cya gahunda zo kugenzura isi. Umwaka w'ishuri ry'ubumenyi rya New York, 1430 (1), 3-43.

Raj, V., Ojha, S., Howarth, FC, Belur, PD, & Subramanya, SB (2018). Ubushobozi bwo kuvura benfotiamine nintego zayo. Isubiramo ryiburayi ryubuvuzi na farumasi, 22 (10), 3261-3273.