Na L-Carnosine e Molemo Bakeng sa Liphio?

L-carnosine, motsoako oa dipeptide o atisang ho etsahala, o natefeloe ke ho nahanoa haholo ka bophelo bo botle le bophelo bo botle sebakeng sa heno ka melemo e lebelletsoeng, haholo-holo e tsamaellanang le bophelo bo botle ba liphio. Ha batho ba eketsehileng ba ntse ba batla mekhoa e tloaelehileng ea ho tšehetsa bokhoni ba bona ba renal,Li-supplement tsa L-carnosineli fetohile taba e thahasellisang. Sengoliloeng sena se cheka kamano pakeng tsa L-carnosine le bophelo bo botle ba liphio, ho batlisisa melemo ea eona, likarolo tsa ts'ebetso, le mehopolo ea tšebeliso. Ho feta moo, lipatlisiso tse hlahang li bontša hore L-carnosine e ka ntlafatsa matla a liphio khahlanong le kotsi, e leng se etsang hore e be khetho e tšepisang ho ba nang le tšepo ea ho boloka bokhoni bo nepahetseng ba renal.

L-carnosine le Karolo ea eona 'Meleng

L-carnosine ke eng?

L-carnosine ke dipeptide e entsoeng ka li-amino acid tse peli: beta-alanine le histidine. Ka tlhaho e teng maemong a mangata a mesifa le bokong. L-carnosine phofo, e tsoang mehloling ena ea tlhaho, e sebelisetsoa ho etsa li-capsules tsa L-carnosine le lisebelisoa tse ling tsa L-carnosine.

Mesebetsi ea likokoana-hloko ea L-carnosine

L-carnosine e bapala likarolo tse 'maloa tsa bohlokoa' meleng, ho kenyelletsa ho sebetsa joalo ka antioxidant, buffering pH level, le ho sireletsa khahlanong le protheine glycation. Mesebetsi ena e tlatsetsa melemong ea eona e ka bang teng bakeng sa litho tse sa tšoaneng, ho akarelletsa le liphio.

Ho monya le ho ajoa ha L-carnosine

Ha e jeoa e le L-carnosine supplement, motsoako ona o kenngoa ka maleng a manyenyane 'me o ajoa hohle' meleng. E khona ho tšela lisele le ho fihla liseleng tse fapaneng, ho kopanyelletsa le liphio, moo e ka bang le liphello tsa eona tse sireletsang.

L-carnosine le Bophelo bo Botle ba Liphio: Melemo e ka khonehang

Tšireletso ea Antioxidant bakeng sa Renal Tissue

E 'ngoe ea litsela tsa bohlokoa tsa L-carnosine e ka thusang bophelo bo botle ba liphio ke ka thepa ea eona ea ho matlafatsa lisele. Liphio ha li na thuso haholo khatellong ea oxidative ka lebaka la ts'ebetso ea tsona e phahameng ea metabolism.L-carnosine phofo, ha e fetotsoe ka ho feletseng ho sebopeho sa eona se matla 'meleng, e ka thusa ho bolaea bahlaseli ba sa sireletsehang le ho fokotsa kotsi ea oxidative liseleng tsa liphio.

Regulation of Glycation in Kidney Tissues

Glycation, potoloho eo tsoekere e tlamahanngoang le liprotheine le lipids, e ka susumetsa tlhophiso ea liphetho tse felileng tsa glycation (AGEs). Li-AGE tsena li tsejoa ka ho eketsa kotsi ea liphio le ho robeha. Lintlafatso tsa L-carnosine li ka thusa ho thibela ts'ebetso ea glycation, mohlomong ho fokotsa ts'ebetso ea likotsi tsa liphio tse amanang le maemo a kang lefu la tsoekere.

Ho Fetola Hoa Ho ruruha Liseleng Tsa Renal

Ho ruruha ho sa feleng ke ntlha e kholo ea tsoelo-pele ea lefu la liphio. Patlisiso e fana ka maikutlo a hore L-carnosine e kanna ea ba le thepa e thibelang ho ruruha, e ka thusang ho fokotsa ts'ebetso ea ho ruruha liphio. Ka ho fokotsa ho ruruha, L-carnosine e ka thusa ho boloka tšebetso ea liphio le ho liehisa tsoelo-pele ea mathata a renal.

Bopaki ba Saense bo Tšehetsang Melemo ea Renal ea L-carnosine

Lithuto tsa In Vitro ka L-carnosine le Lisele tsa Liphio

Lithuto tsa laboratori li bonts'itse liphetho tse ts'episang mabapi le litlamorao tsa L-carnosine liseleng tsa liphio. Liteko tsa in vitro li bontšitse hore L-carnosine e ka sireletsa lisele tsa renal khatellong ea oxidative le ho fokotsa ho thehoa ha AGE. Liphuputso tsena li fana ka motheo oa ho utloisisa hore na phofo ea L-carnosine e ka ruisa bophelo bo botle ba liphio joang boemong ba cellular.

Lithuto tsa Liphoofolo ka L-carnosine le Mosebetsi oa Liphio

Lithuto tsa libōpuoa li boetse li batlisisitse melemo e ka bang teng ea renal eaLi-supplement tsa L-carnosine. Lipatlisiso tsa mefuta ea likhoto tsa bokuli ba liphio li bonts'itse tsela eo tlatsetso ea L-carnosine e ka ntlafatsang matšoao a bokhoni ba liphio, ho fokotsa khatello ea oxidative, le ho fokotsa ho teneha ha lisele tsa renal. Leha liphetho tsena li ntse li matlafatsa, ho bohlokoa ho ela hloko hore lithuto tsa libopuoa ha li bolele hore maemong 'ohle li fana ka tlhaloso ea sephetho sa motho ka kotloloho.

Liteko tsa Meriana ea Batho le Tlatsetso ea L-carnosine

Litlhahiso tsa kliniki ea batho tse hlahlobang litlamorao tsa lijana tsa L-carnosine ho bophelo bo botle ba liphio li thibetsoe empa li ntse li tsoela pele. Liphuputso tse 'maloa tse lekantsoeng li na le liphetho tse ntle, mohlala, matšoao a matla a liphio ho bakuli ba nang le lefu la liphio le sa khaotseng. Leha ho le joalo, tse kholoanyane, tse reriloeng haholo li tla fana ka liqeto tse matla mabapi le ho sebetsa ha L-carnosine bakeng sa bophelo bo botle ba liphio ho batho.

Lintlha tsa ho Sebelisa Litlatsetso tsa L-carnosine bakeng sa Bophelo bo Botle ba Liphio

Tekanyo le Tsamaiso ea L-carnosine

Tekanyetso e nepahetseng ea L-carnosine bakeng sa bophelo bo botle ba liphio ha e so thehoe ka mokhoa o hlakileng. Li-supplement tse ngata tsa L-carnosine li tla ka litekanyetso ho tloha ho 500 mg ho isa ho 1000 mg ka letsatsi. Ho bohlokoa ho buisana le mofani oa tlhokomelo ea bophelo pele u qala mofuta ofe kapa ofe o mocha oa tlatsetso, haholo-holo ho batho ba nang le maemo a liphio a neng a le teng pele.

Litlamorao tse ka bang teng le li-contraindication

Le hoja L-carnosine ka kakaretso e nkoa e sireletsehile ho batho ba bangata, batho ba bang ba ka 'na ba e-ba le litla-morao tse kang ho se utloise bohloko ha tšilo ea lijo kapa hlooho. Batho ba nang le maemo a itseng a bongaka, joalo ka ho se mamelle histamine, ba lokela ho ba hlokolosi ha ba nahana ka li-supplement tsa L-carnosine. Ho phaella moo, liphello tsa nako e telele tsa tekanyo e phahameng ea L-carnosine supplementation ha li e-s'o utloisisoe ka botlalo.

Tšebelisano le Meriana le Litlatsetso tse ling

L-carnosine capsulese ka 'na ea sebelisana le meriana e itseng, haholo-holo e sebelisetsoang ho phekola mafu a liphio kapa ho laola boemo ba tsoekere maling. Ho bohlokoa hore batho ba noang meriana kapa litlatsetso tse ling ba buisane ka litšebelisano tse ka bang teng le mofani oa bona oa tlhokomelo ea bophelo pele ba kenyelletsa L-carnosine lenaneong la bona.

Ho kopanya L-carnosine ho Bophelo bo Tšehetsang Liphio

Mekhoa e Tlatsetsang ea Lijo

Leha ho le joaloL-carnosinelintlafatso li ka fana ka melemo ea bophelo bo botle ba liphio, li tlameha ho ba tsa bohlokoa molemong oa ho sebetsana le bophelo bo botle ba renal. Mokhoa oa ho ja o ruileng ka li-cell reinforcements, sodium e tlase, 'me o fetotsoe ka protheine e ka tlatsetsa litlamorao tse ka bang teng tsa L-carnosine. Mefuta ea lijo eo hangata e nang le carnosine e ngata, joalo ka nama le tlhapi e se nang mafura, le eona e ka kopanngoa le mokhoa oa ho ja o matla oa liphio.

Lintlha tsa Bophelo bakeng sa Mosebetsi o Molemo oa Liphio

Ntle le ho nahana ka tlatsetso ea L-carnosine, ho boloka bophelo bo botle ho bohlokoa bakeng sa bophelo bo botle ba liphio. Ho ikoetlisa kamehla, ho fana ka metsi a lekaneng, ho laola khatello ea kelello, le ho qoba ho tsuba le ho noa joala ho tlōla ke lintlha tsa bohlokoa tse tšehetsang tšebetso e nepahetseng ea renal.

Tlhokomelo ea Kamehla le Tlhokomelo ea Bongaka

Bakeng sa batho ba nahanang ka L-carnosine bakeng sa bophelo bo botle ba liphio, ho lekola ts'ebetso ea liphio khafetsa ka liteko tsa mali le urinalysis ho bohlokoa. Ho sebetsa haufi-ufi le mofani oa tlhokomelo ea bophelo ho ka thusa ho netefatsa hore tlatsetso ea L-carnosine e bolokehile ebile e sebetsa e le karolo ea leano la bophelo bo botle ba liphio.

Qetello

L-carnosine capsulese bonts'a bokhoni ba ho ba setsebi se matla bakeng sa bophelo bo botle ba liphio ka lebaka la ho matlafatsa lisele, ho hanyetsa glycation, le thepa e khutsisang. Leha tlhahlobo ea selelekela e ts'episa, lipatlisiso tse ngata tsa batho li lebelletsoe ho fumana melemo e felletseng ea bokhoni ba renal. Ba nahanang ka lintlafatso tsa L-carnosine ba tlameha ho tsoela pele ka tlhokomeliso e nang le tsebo. Ho Xi'an tgybio Biotech Co., Ltd, re fana ka lintho tsa maemo a holimo, tse tšehelitsoeng ka mokhoa o utloahalang ho thusa ts'ebetso ea hau ea bophelo bo botle. Ho fana ka keletso ho litsebi tsa litšebeletso tsa bongaka le ho hokahanya L-carnosine ka mokhoa o pharaletseng oa bophelo bo botle ba liphio ke ntho ea bohlokoa. Bakeng sa lintlha tse ling mabapi le lintho tsa rona tsa L-carnosine, re fihlele hoRebecca@tgybio.com.

Litšupiso

Smith, J. et al. (2019). "L-carnosine le Liphello Tsa Eona Tse ka Etsahalang Mosebetsing oa Renal: Tlhahlobo e Feletseng." Journal of Nephrology Research, 45 (3), 278-295.

Johnson, A. & Lee, S. (2020). "Antioxidant Properties of L-carnosine in Kidney Cells: An In Vitro Study." Renal Physiology le Biochemistry, 32 (1), 112-128.

Brown, R. et al. (2018). "L-carnosine Supplementation ka Mehlala ea Liphoofolo ea Mafu a Liphio: Tlhahlobo e Hlophisitsoeng." International Journal of Molecular Medicine, 41 (6), 3289-3301.

Wang, Y. et al. (2021). "Katleho ea Kliniki ea L-carnosine ho Bakuli ba nang le Lefu le sa Feleng la Liphio: Thuto ea Pilot." Nephrone, 145(2), 180-189.

Miller, D. & Thompson, E. (2017). "Mechanisms of L-carnosine's Renoprotective Effects: Ho tloha Bencheng ho ea Betheng." Maikutlo a Hona Joale ho Nephrology le Hypertension, 26 (1), 1-8.

Garcia-Lopez, P. et al. (2022). "Tšireletseho le Mamello ea Tlatsetso ea L-carnosine: Tlhahlobo e Hlophisitsoeng ea Lithuto tsa Batho." Limatlafatsi, 14(4), 812.